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GOT1 inhibitor-1

CAS No. 732973-87-4

GOT1 inhibitor-1 ( GOT1 inhibitor 2c )

Catalog No. M24741 CAS No. 732973-87-4

GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GOT1 inhibitor-1
  • Note
    Research use only, not for human use.
  • Brief Description
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • Description
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • Synonyms
    GOT1 inhibitor 2c
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GOT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    732973-87-4
  • Formula Weight
    354.8
  • Molecular Formula
    C19H19ClN4O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120mg/ml(338.19mM; need ultrasonic)
  • SMILES
    O=C(Nc(cc1)ccc1Cl)N(CC1)CCN1c1c(cc[nH]2)c2ccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Anglin J , Zavareh R B , Sander P N , et al. Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma[J]. Bioorganic & Medicinal Chemistry Letters, 2018:S0960894X18303743.
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