GOT1 inhibitor-1

CAS No. 732973-87-4

GOT1 inhibitor-1 ( GOT1 inhibitor 2c )

Catalog No. M24741 CAS No. 732973-87-4

GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 In Stock
10MG 295 In Stock
25MG 502 In Stock
50MG 709 In Stock
100MG 1008 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GOT1 inhibitor-1
  • Note
    Research use only, not for human use.
  • Brief Description
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • Description
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • Synonyms
    GOT1 inhibitor 2c
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GOT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    732973-87-4
  • Formula Weight
    354.8
  • Molecular Formula
    C19H19ClN4O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120mg/ml(338.19mM; need ultrasonic)
  • SMILES
    O=C(Nc(cc1)ccc1Cl)N(CC1)CCN1c1c(cc[nH]2)c2ccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Anglin J , Zavareh R B , Sander P N , et al. Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma[J]. Bioorganic & Medicinal Chemistry Letters, 2018:S0960894X18303743.
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